Objective

To synthesize 1 Ugi product following the EXPLAN005 .

Procedure

As described in Explan005. This is a repeat of Exp130-4

Comp ID/ Lib Rank	Methanol Added	Aldehyde	Amine	Carboxylic Acid	Isocyanide	Ppt Yes/No
130-4	500uL	B-napthaldehyde (0.53mmol, 82.8mg)	furfurylamine (0.53mmol, 46.8uL)	formic acid (0.53mmol, 20.0uL)	benzylisocyanide (0.53mmol, 64.4uL)

Results

Discussion

Conclusion

Log

2007-11-14

11:45 Weighed B-naphthaldehyde(0.53mmol,82.8mg)
11:55 Added 500 uL of Methanol to one dram vial.
12:00 Added furfurylamine (0.53mmol, 46.8uL), vortexed solution for 15 seconds.
12:02 Added B-napthaldehyde (0.53mmol, 82.8mg) and vortexed solution for 15 seconds.
12:04 Added formic acid (0.53mmol, 20.0uL) and vortexed solution for 15 seconds.
12:06 Added benzylisocyanide (0.53mmol, 64.4uL) and vortexed solution for 15 seconds.\
12:13 Took picture of solution after all reagents were combined.

Tags

benzylisocyanide InChI=1/C8H7N/c1-9-7-8-5-3-2-4-6-8/h2-6H,7H2
B-naphthaldehyde InChI=1/C11H8O/c12-8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H
formic acid InChI=1/CH2O2/c2-1-3/h1H,(H,2,3)
furfurylamine InChI=1/C5H7NO/c6-4-5-2-1-3-7-5/h1-3H,4,6H2